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This happens because opioids fit into specific receptors in the brain that have an effect on breathing. Opioid overdoses happen when there are so many opioids overloading the body that the brain shuts down breathing. If you feel the need to take more of the drug than was prescribed to you – talk to your doctor! What is an overdose? However, the body soon begins to develop a tolerance for the medication, so that the same dose of medication offers less pain relief. When taken as directed, opioids can be very effective in relieving pain. They can also affect the pleasure center of your brain, causing a sense of euphoria. Opioids work by blocking your brain’s sensation of pain. Opioid drugs include heroin as well as medications available by prescription such as oxycodone and methadone. But, these drugs also have the potential to produce physical dependence, abuse, and addiction. Opioid drugs are important medications for the treatment of pain, opioid dependence, and terminal illness.
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